Selected Preprints and Publications
2025
Burgess J*, Nirschl JJ*, Bravo-Sánchez L*, Lozano A, Gupte SR, Galaz-Montoya JG, Zhang Y, Su Y, Bhowmik D, Coman Z, Hasan SM, Johannesson A, Leineweber WD, Nair MG, Yarlagadda R, Zuraski C, Chiu W, Cohen S, Hansen JN, Leonetti MD, Liu C, Lundberg E, and Yeung-Levy S. (2025). MicrovQA: a multimodal reasoning benchmark for microscopy-based scientific research. Arxiv. *Co-first author. [link].
Friday CM, Stephens IO, Smith CT, Lee S, Satish D, Devaney NA, Cohen S, Morganti JM, Gordon SM, and Johnson LA. (2025). APOE4 alters the lipid droplet proteome and modulates droplet dynamics. bioRxiv. [link]
2024
Rhoads SN, Dong W, Hsu CS, Mfulama NR, Ragusa JV, Ye M, Henrie A, Zanellati MC, Diering GH, Cohen TJ#, and Cohen S#. (2024). Neurons and astrocytes have distinct organelle signatures and responses to stress. bioRxiv. #Co-corresponding. [link]
Miner GE and Cohen S. (2024). Protocol for monitoring fatty acid trafficking from lipid droplets to mitochondria in cultured cells. STAR Protocols 5: 103236. [link]
Miner GE, Smith SY, Showalter WK, So CM, Ragusa JV, Powers AE, Zanellati MC, Hsu CS, Marchan MF, and Cohen S. (2024). ContactFP: a dimerization-dependent fluorescent protein toolkit for visualizing membrane contact site dynamics. Contact 2024: 7 [link]
Windham IA, Powers AE, Ragusa JV, Wallace ED, Zanellati MC, Williams VH, Wagner CH, White KK, and Cohen S. (2024). APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size. Journal of Cell Biology 223: e202305003 [link]
–Spotlight by Feringa and van der Kant
Burgess J, Nirschl JJ, Zanellati MC, Lozano A, Cohen S, and Yeung-Levy S. (2024). Orientation-invariant autoencoders learn robust representations for shape profiling of cells and organelles. Nature Communications 15: 1022 [link]
2023
Windham IA and Cohen S. (2023). The cell biology of APOE in the brain. Trends in Cell Biology Oct 5:S0962-8924(23)000196. [link]
Miner GE, So SM, Edwards W, Ragusa JV, Wine JT, Wong Gutierrez D, Airola MV, Herring LE, Coleman RA, Klett EL, and Cohen S. (2023). PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport. Developmental Cell 58(14): 1250-1265. [link]
2022
Zanellati MC and Cohen S. (2022). The endosome as engineer. Science 378(6625): 1173-1174. Perspective on Jang et al., 2022. [link]
Pantazis CB, A Yang, E Lara, JA McDonough, C Blauwendraat, L Peng…MC Zanellati, R Basundra, M Deshmukh, S Cohen…WC Skarnes, MR Cookson, ME Ward, and FT Merkle. (2022). A reference induced pluripotent stem cell line for large-scale collaborative studies. Cell Stem Cell 29(12): 1685-1702. [link]
Windham IA and Cohen S. (2022). Lipid droplets go through a (liquid crystalline) phase. Journal of Cell Biology 221(11): e202210008. Spotlight on Rogers et al., JCB. [link]
2021
Joshi AS#, Ragusa JV, Prinz WA, and Cohen S#. (2021). Multiple C2 domain-containing transmembrane proteins promote lipid droplet biogenesis and growth at specialized ER subdomains. Molecular Biology of the Cell 32(12): 1147-1157. #Co-corresponding authors. [link].
2020
Arribat Y, Grepper D, Lagarrigue S, Qi T, Cohen S, and Amati F. (2020). Spastin mutations impair coordination between lipid droplet dispersion and reticulum. PLOS Genetics 16(4): e1008665. [link].
2019
Joshi AS# and Cohen S#. (2019). “Lipid droplet and peroxisome biogenesis: do they go hand-in-hand?” Frontiers in Cell and Developmental Biology. 7: 92. Review article. #Co-corresponding authors. [link].
2018
Cohen S. (2018). Lipid droplets as organelles. International Review of Cell and Molecular Biology 337: 83-110. Review Article. [link]
Pre-UNC
Cohen S, Valm AM, and Lippincott-Schwartz J. (2018). Interacting organelles. Current Opinion in Cell Biology 53: 84-91. [link].
Cohen S*, Valm AM*, and Lippincott-Schwartz J. Multispectral live-cell imaging. (2018). Current Protocols in Cell Biology 79(1): e46. *Co-first author. [link].
Valm AM*, Cohen S*, Legant WR, Melunis J, Hershberg U, Wait E, Cohen AR, Davidson MW, Betzig E, and Lippincott-Schwartz J. (2017). Applying systems-level spectral imaging and analysis to reveal the organelle interactome. Nature 546: 162-167. *Co-first author. [link]
–News and Views by Shim
-Recommended by Faculty of 1000
-Featured by Gizmodo
Rambold AS*, Cohen S*, and Lippincott-Schwartz J. (2015). Fatty acid trafficking in starved cells: regulation by lipid droplet lipolysis, autophagy, and mitochondrial fusion dynamics. Developmental Cell 32: 678-692. *Co-first author. [link]
-Preview by Walch, Copic, and Jackson
